The SMCL NGS Hub offers Illumina 5-base whole-genome sequencing (WGS), enabling the simultaneous analysis of genomic variation and DNA methylation within a single assay. With support from Illumina, we have successfully implemented the 5-base prep across a broad range of clinical sample types, including low-input and lower-quality DNA, demonstrating robust and consistent performance. We are highly impressed by the reliability and data quality of this technology and are already supporting a growing number of projects. Please contact us to discuss how this approach could enhance your study.